Assay 1: The ED50 was determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is 0.1 ng/ml corresponding to a specific activity of 1 x 107 units/mg. Assay 2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is 1.0 ng/ml, corresponding to a specific activity of 1 x 106 units/mg.
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