CD33 antibody [WM53], IgG1, Unconjugated, Mouse, Monoclonal

Product Overview

• Article Name: CD33 antibody [WM53], IgG1, Unconjugated, Mouse, Monoclonal
• Biozol Catalog Number: GTX00477
• Supplier Catalog Number: GTX00477
• Alternative Catalog Number: GTX00477-100
• Manufacturer: GeneTex
• Host: Mouse
• Category: Antikörper
• Application: FC, ICC, IHC-Fr, IP, MS, WB
• Species Reactivity: Human, Primate
• Immunogen: Human AML cells
• Conjugation: Unconjugated
• Alternative Names: CD33 , CD33 molecule , SIGLEC3 , p67

Product Description

CD33, also known as Siglec-3 or gp67, is a 67 kDa glycosylated cell surface receptor that mediates cell-cell interactions and maintains immune cells in a resting state. Although CD33 is found on some lymphoid subsets, it is highly expressed on myeloid lineage cells, and is commonly used for the diagnosis of acute myeloid leukemia (AML). CD33 is an established target for therapy, with CD33-positive blasts detected in almost 90 percent of patients presenting with AML.

Product Properties

• Clonality: Monoclonal
• Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
• Clone Designation: [WM53]
• Molecular Weight: 40
• Isotype: IgG1
• NCBI: 945
• UniProt: P20138
• Buffer: PBS, 15mM Sodium azide.
• Purity: Protein A purified
• Form: Liquid