CD3 epsilon antibody [145-2C11] (PerCP-Cy5.5), IgG1, PerCP/Cy5.5, Hamster, Monoclonal

Product Overview

• Article Name: CD3 epsilon antibody [145-2C11] (PerCP-Cy5.5), IgG1, PerCP/Cy5.5, Hamster, Monoclonal
• Biozol Catalog Number: GTX00603-11
• Supplier Catalog Number: GTX00603-11
• Alternative Catalog Number: GTX00603-11-100
• Manufacturer: GeneTex
• Host: Hamster
• Category: Antikörper
• Application: FC
• Species Reactivity: Mouse
• Immunogen: Mouse BM10-37 cytotoxic T lymphocytes
• Conjugation: PerCP/Cy5.5
• Alternative Names: CD3 antigen, epsilon polypeptide , AI504783 , CD3 , CD3epsilon , T3e

Product Description

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Product Properties

• Clonality: Monoclonal
• Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
• Clone Designation: [145-2C11]
• Isotype: IgG1
• NCBI: 12501
• UniProt: P22646
• Buffer: 10mM NaH2PO4, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
• Form: Liquid