Fas Ligand antibody [NOK-1], IgG1, Unconjugated, Mouse, Monoclonal
Catalog Number:
GTX01476
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| Article Name: | Fas Ligand antibody [NOK-1], IgG1, Unconjugated, Mouse, Monoclonal |
| Biozol Catalog Number: | GTX01476 |
| Supplier Catalog Number: | GTX01476 |
| Alternative Catalog Number: | GTX01476-100 |
| Manufacturer: | GeneTex |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | ELISA, FC, IP, NeA, WB |
| Species Reactivity: | Human |
| Conjugation: | Unconjugated |
| Alternative Names: | Fas ligand , ALPS1B , APT1LG1 , APTL , CD178 , CD95L , FASL , FASLG , TNFSF6 , TNLG1A , fasL , Fas Ligand , Fasligand , CD95 ligand |
| The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF-alpha family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein. |
| Application Notes: | *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications. |
