FOXP3 antibody [MF23] (PE), IgG2b, Rat, Monoclonal

Catalog Number: GTX01488-08
Article Name: FOXP3 antibody [MF23] (PE), IgG2b, Rat, Monoclonal
Biozol Catalog Number: GTX01488-08
Supplier Catalog Number: GTX01488-08
Alternative Catalog Number: GTX01488-08-100
Manufacturer: GeneTex
Host: Rat
Category: Antikörper
Application: FC
Species Reactivity: Mouse
Conjugation: PE
The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
Clonality: Monoclonal
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Clone Designation: [MF23]
Isotype: IgG2b
NCBI: 20371
UniProt: Q99JB6
Buffer: 10mM NaH2PO4, 150mM NaCl, 0.1% Gelatin, 0.09% Sodium azide.
Form: Liquid
Application Notes: *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.