CXCR7 antibody [C1C2], Internal, Unconjugated, Rabbit, Polyclonal

Product Overview

• Article Name: CXCR7 antibody [C1C2], Internal, Unconjugated, Rabbit, Polyclonal
• Biozol Catalog Number: GTX100027
• Supplier Catalog Number: GTX100027
• Alternative Catalog Number: GTX100027-25, GTX100027-100
• Manufacturer: GeneTex
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, FC, ICC, IHC-Fr, IHC-P, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human CXCR7. The exact sequence is proprietary.
• Conjugation: Unconjugated
• Alternative Names: atypical chemokine receptor 3 , CMKOR1 , CXC-R7 , CXCR-7 , CXCR7 , GPR159 , RDC-1 , RDC1

Product Description

CXCR7 antibody recognizes C-X-C chemokine receptor type 7 (CXCR7), now known as atypical chemokine receptor 3 (ACKR3). This chemokine receptor (with a predicted molecular weight of 41 kDa) binds the chemokines CXCL11 and CXCL12 and other non-chemokine ligands such as adrenomedullin and MIF. ACKR3 plays important roles in cardiovascular and neuronal development and acts as a scavenger receptor to regulate both chemokine- and opioid peptide-dependent signaling.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.14 mg/ml (Please refer to the vial label for the specific concentration.)
• Molecular Weight: 41
• Sensitivity: KO/KD validation is based on published data (PMID: 32366833).
• NCBI: 57007
• UniProt: P25106
• Buffer: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
• Form: Liquid

Application Notes

• Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.