PARP antibody (more specifically, PARP1 antibody) detects poly(ADP-ribose) polymerase (PARP)-1, which is involved in various biological mechanisms such as DNA repair, genomic stability, and programmed cell death. Preclinical and clinical studies showed that PARP inhibition is an effective anti-tumor modality, and thus PARP inhibitors have become essential components of various chemotherapeutic regimens against many malignancies.
Clonality:
Polyclonal
Concentration:
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Molecular Weight:
113
Sensitivity:
This antibody is specific for human PARP1 protein, and it does not cross react with human PARP2 and PARP3 protein.,IP/MS validation is based on published data (PMID: 30377409).
WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
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