Pexiganan, CAS [[147664-63-9]]

Product Overview

• Article Name: Pexiganan, CAS [[147664-63-9]]
• Biozol Catalog Number: ISC-AM-310
• Supplier Catalog Number: AM-310
• Alternative Catalog Number: ISC-AM-310
• Manufacturer: Isca Biochemicals
• Category: Biochemikalien
• Alternative Names: MSI 78

Product Description

Pexiganan (MSI 78) is a synthetic cationic peptide and an analogue of magainin 2, the host defence peptide isolated from the skin of the African frog Xenopus laevis. Pexiganan exhibits in vitro broad-spectrum antibacterial activity against many gram-positive and gram-negative, anaerobic and aerobic bacteria and is the first AMP developed into an antibacterial drug and the best-studied AMP to date for therapeutic purposes. Pexiganan shows a barrel-stave type mechanism of membrane disruption or channel formation and exerts its antibacterial effect by forming toroidal pores in bacterial membranes.

Product Properties

• Molecular Weight: 2477.21
• NCBI: 1998
• Purity: >95% by hplc
• Form: Freeze dried solid
• Sequence: H-Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Ile-Leu-Lys-Lys-NH2
• CAS Number: [147664-63-9]
• Formula: C122H210N32O22
• Target: Antibacterials

Application Notes

• Application Notes: ProductType: Antimicrobial peptides