Amylin, CAS [[122384-88-7]]

Product Overview

• Article Name: Amylin, CAS [[122384-88-7]]
• Biozol Catalog Number: ISC-CG-040
• Supplier Catalog Number: CG-040
• Alternative Catalog Number: ISC-CG-040
• Manufacturer: Isca Biochemicals
• Category: Biochemikalien
• Alternative Names: Islet amyloid polypeptide, IAPP

Product Description

Amylin (also known as islet amyloid polypeptide, or IAPP) is a centrally acting, neuroendocrine hormone and member of the calcitonin family of peptides, synthesized and cosecreted with insulin in the beta cells of pancreatic islets. Amylin inhibits glucagon secretion, delays gastric emptying and acts as a satiety agent. Amylin is a major component of the islet amyloid deposited in the pancreas in type 2 diabetes mellitus and may contribute to beta-cell degeneration.

Product Properties

• Molecular Weight: 3903.33
• NCBI: 1995
• Purity: >95% by hplc
• Form: Freeze dried solid
• Sequence: H-Lys-Cys*-Asn-Thr-Ala-Thr-Cys*-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (disulfide bridge between cysteines 2 and 7)
• CAS Number: [122384-88-7]
• Formula: C165H261N51O55S2
• Target: Calcitonin and related receptors

Application Notes

• Application Notes: ProductType: Peptides