Amylin (8-37) (human), CAS [[135702-23-7]]

Product Overview

• Article Name: Amylin (8-37) (human), CAS [[135702-23-7]]
• Biozol Catalog Number: ISC-CG-050
• Supplier Catalog Number: CG-050
• Alternative Catalog Number: ISC-CG-050
• Manufacturer: Isca Biochemicals
• Category: Biochemikalien
• Alternative Names: IAPP (8-37), Islet Amyloid Polypeptide (8-37) (human)

Product Description

Amylin (8-37) (human) is a peptide fragment of amylin with the first seven amino acids removed, including the disulphide bridge, that acts as an amylin receptor antagonist. Amylin (8-37) (human) inhibits osteoblast proliferation induced by full-length human amylin and has no agonist activity at amylin receptors. Amylin (8-37) (human) induces formation of polymorphic fibrils containing coiled and laterally-associated sheet structures and is cytotoxic to RINm5F islet beta-cells in vitro when used at a concentration of 25 µM, an effect that is inversely correlated with mature fibril content.

Product Properties

• Molecular Weight: 3183.49
• NCBI: 1991
• Purity: >95% by hplc
• Form: Freeze dried solid
• Sequence: H-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
• CAS Number: [135702-23-7]
• Formula: C138H216N42O45
• Target: Calcitonin and related receptors

Application Notes

• Application Notes: ProductType: Peptides