GLP-1 (7-36) amide (human, rat), CAS [[107444-51-9]]
Biozol Catalog Number:
ISC-GH-050
Supplier Catalog Number:
GH-050
Alternative Catalog Number:
ISC-GH-050
Manufacturer:
Isca Biochemicals
Category:
Biochemikalien
GLP-1 (7-36) amide is a potent insulinotropic incretin peptide hormone produced as a result of proteolytic post-translational modification of proglucagon in L-cells of the lower intestine. GLP-1 (7-36) amide displays high affinity for GLP-1 receptors expressed in rat insulinoma-derived RINm5F cells with a Kd of 204 pM. GLP-1 (7-36) amide stimulates insulin gene transcription and secretion in pancreatic beta-cells, displays antiapoptotic effects in hippocampal neurons and reduces food intake in fasted rats following central administration.
