MBP (4-14), also known as Myelin Basic Protein Fragment (4-14), is a synthetic peptide having the sequence surrounding Ser(8) of myelin basic protein, and is a highly selective substrate for protein kinase C (PKC). MBP (4-14) is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase. MBP (4-14) is routinely used for the assay of protein kinase C.
