Etomoxir is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1). Etomoxir inhibits beta-oxidation in mitochondria and also inhibits cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells, and is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease, diabetes, and cancer.
Molecular Weight:
320.74
Purity:
98% by HPLC, NMR conforms
Form:
White solid
Sequence:
(R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt
CAS Number:
[828934-41-4]
Formula:
C15H18ClO4 € Na
Target:
Transferases
Application Notes:
ProductType: Small molecules
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