Biotinylated Human/Mouse/Rat Activin A Protein (ACV-HM401B)

Product Overview

• Article Name: Biotinylated Human/Mouse/Rat Activin A Protein (ACV-HM401B)
• Biozol Catalog Number: KAB-ACV-HM401B
• Supplier Catalog Number: ACV-HM401B
• Alternative Catalog Number: KAB-ACV-HM401B-100UG, KAB-ACV-HM401B-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Biotin
• Alternative Names: INHBA, Activin A,

Product Description

Recombinant Biotinylated Human/Mouse/Rat Activin A Protein is expressed from HEK293 with Avi tag at the C-terminus. It contains Gly311-Ser426.

Product Properties

• Molecular Weight: The protein has a predicted MW of 14.78 kDa. Due to glycosylation, the protein migrates to 15-18 kDa under reduced (R) condition, and 23-30 kDa under Non reduced (N) condition based on Bis-Tris PAGE result.
• Tag: C-Avi
• UniProt: P08476
• Buffer: Supplied as 0.22 µm filtered solution in 4 mM HCL.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE
• Form: Liquid
• Sequence: Gly311-Ser426
• Target: Activin A

Images

Biotinylated Human/Mouse/Rat Activin A on Bis-Tris PAGE under reduced (R) condition and Non reduced (N) condition. The purity is greater than 95%.

Immobilized Human/Cynomolgus Activin RIIB, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Human/Mouse/Rat Activin A, Avi Tag with the EC50 of 2.1 ng/ml determined by ELISA (QC Test).

Serial dilutions of Bimagrumab were added into Human/Cynomolgus Activin RIIB, His Tag : Biotinylated Human/Mouse/Rat Activin A, Avi Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 0.14ug/ml.

Immobilized Human/Cynomolgus Activin RIIA, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Activin A, Avi Tag with the EC50 of 10.4ng/ml determined by ELISA.