Recombinant Human/Cynomolgus Activin RIIB/ACVR2B Protein is expressed from HEK293 with mFc (IgG1) tag at the C-terminus., It contains Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus).
Molecular Weight:
The protein has a predicted MW of 39.32 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Expression System:
HEK293
Purity:
> 95% as determined by Bis-Tris PAGE
Form:
Lyophilized
Sequence:
Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus)
Target:
Activin RIIB/ACVR2B
Human/Cynomolgus Activin RIIB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Immobilized Human Activin A, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, mFc Tag with the EC50 of 41.4 ng/ml determined by ELISA (QC Test).
Immobilized Human/Cynomolgus Activin RIIB, mFc Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-Activin RIIB Antibody, hFc Tag with the EC50 of 6.9 ng/ml determined by ELISA.
Immobilized Human/Mouse/Rat GDF-8, No Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, mFc Tag with the EC50 of 20.8ng/ml determined by ELISA.
* VAT and and shipping costs not included. Errors and price changes excepted
