Human IL-17R alpha/CD217 Protein (CD7-HM1RA)

Product Overview

• Article Name: Human IL-17R alpha/CD217 Protein (CD7-HM1RA)
• Biozol Catalog Number: KAB-CD7-HM1RA
• Supplier Catalog Number: CD7-HM1RA
• Alternative Catalog Number: KAB-CD7-HM1RA-100UG, KAB-CD7-HM1RA-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: CD217, CDw217, IL-17RA, IL17R, CANDF5, IL-17R, IL-17R-alpha, IL17Ralpha

Product Description

Recombinant Human IL-17R alpha/CD217 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu33-Trp320.

Product Properties

• Molecular Weight: The protein has a predicted MW of 34.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
• Tag: C-His
• UniProt: Q96F46
• Buffer: Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: Leu33-Trp320
• Target: IL-17R alpha/CD217

Images

Human IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-17R alpha is greater than 95% as determined by SEC-HPLC.

Human IL-17R alpha, His Tag immobilized on CM5 Chip can bind Human IL-17A, His Tag with an affinity constant of 1.57 nM as determined in SPR assay (Biacore T200).

Immobilized Human IL-17R alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.44ug/ml determined by ELISA (QC Test).