Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)

Product Overview

• Article Name: Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
• Biozol Catalog Number: KAB-CTL-CM141
• Supplier Catalog Number: CTL-CM141
• Alternative Catalog Number: KAB-CTL-CM141-100UG, KAB-CTL-CM141-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Alternative Names: CTLA4, CD152, ICOS, CELIAC3, GRD4, GSE, ALPS5, IDDM12

Product Description

Recombinant Cynomolgus CTLA-4/CD152 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala37-Ser160.

Product Properties

• Molecular Weight: The protein has a predicted MW of 14.4 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
• Tag: C-His
• UniProt: G7PL88
• Buffer: Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: Ala37-Ser160
• Target: CTLA-4/CD152

Images

Cynomolgus CTLA-4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus CTLA-4 is greater than 95% as determined by SEC-HPLC.

Immobilized Cynomolgus CTLA-4, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CTLA-4 Antibody, hFc Tag with the EC50 of 11.2ng/ml determined by ELISA.

Cynomolgus B7-1, His Tag immobilized on CM5 Chip can bind Cynomolgus CTLA-4, His Tag with an affinity constant of 9.90 nM as determined in SPR assay (Biacore T200).

Immobilized Cynomolgus CTLA-4, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus B7-1, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA (QC Test).