Human pro GDF-8 Protein (GDF-HM118)

Product Overview

• Article Name: Human pro GDF-8 Protein (GDF-HM118)
• Biozol Catalog Number: KAB-GDF-HM118
• Supplier Catalog Number: GDF-HM118
• Alternative Catalog Number: KAB-GDF-HM118-100UG, KAB-GDF-HM118-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Myostatin, GDF8, Mstn, GDF-8, Myostatin

Product Description

Recombinant Human pro GDF-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn24-Ser375.

Product Properties

• Molecular Weight: The protein has a predicted MW of 41.19 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.
• Tag: N-His
• UniProt: O14793
• Buffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: Asn24-Ser375
• Target: GDF-8

Images

The purity of Human pro GDF-8 is greater than 95% as determined by SEC-HPLC.

Human pro GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Human pro GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Apitegromab, hFc Tag with the EC50 of 23.4ng/ml determined by ELISA.

Immobilized Human pro GDF-8, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 35.9ng/ml determined by ELISA.

Loaded Apitegromab, hFc Tag on ProA-Biosensor can bind Human pro GDF-8, His Tag with an affinity constant of 25.10nM as determined in BLI assay (Gator Prime).