Human IL-11 Protein (IL1-HM111)

Product Overview

• Article Name: Human IL-11 Protein (IL1-HM111)
• Biozol Catalog Number: KAB-IL1-HM111
• Supplier Catalog Number: IL1-HM111
• Alternative Catalog Number: KAB-IL1-HM111-100UG, KAB-IL1-HM111-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Interleukin-11,IL11,Adipogenesis inhibitory factor,AGIF,INN: Oprelvekin,Oprelvekin,IL-11Oprelvekin,interleukin 11,interleukin-11

Product Description

Recombinant Human IL-11 Protein is expressed from HEK293 with His tag at the N-Terminus, It contains Pro22-Leu199.

Product Properties

• Molecular Weight: The protein has a predicted MW of 20.24 kDa. Due to glycosylation, the protein migrates to 21-25 kDa based on Bis-Tris PAGE result.
• Tag: N-His
• UniProt: P20809
• Buffer: Lyophilized from 0.22 µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: Pro22-Leu199
• Target: IL-11

Images

Human IL-11 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-11 is greater than 95% as determined by SEC-HPLC.

Human IL-11R alpha, His Tag immobilized on CM5 Chip can bind Human IL-11, His Tag with an affinity constant of 1.86 nM as determined in SPR assay (Biacore T200).

Immobilized Human IL-11, His Tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for Human IL-11 R alpha, hFc Tag with the EC50 of 8.1 ng/ml determined by ELISA (QC Test).

Measured in a cell proliferation assay using TF-1 cells. The ED50-for this effect is typically 1-8 ng/mL.