Human IL-31 RA Protein (ILR-HM2RA)

Product Overview

• Article Name: Human IL-31 RA Protein (ILR-HM2RA)
• Biozol Catalog Number: KAB-ILR-HM2RA
• Supplier Catalog Number: ILR-HM2RA
• Alternative Catalog Number: KAB-ILR-HM2RA-100UG, KAB-ILR-HM2RA-500UG
• Manufacturer: KactusBio
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: IL-31RA, IL-31R-alpha, Gp130-like receptor, CRL3, GPL, ZcytoR17, GLM-R, CRL3Glmr, GLM-RMGC125346, PRO21384

Product Description

Recombinant Human IL-31 RA Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ala20-Glu519.

Product Properties

• Molecular Weight: The protein has a predicted MW of 83.8 kDa. Due to glycosylation, the protein migrates to 110-135 kDa based on Bis-Tris PAGE result.
• Tag: C-hFc (IgG1)
• UniProt: Q8NI17
• Buffer: Lyophilized from 0.22µm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Expression System: HEK293
• Purity: > 95% as determined by Bis-Tris PAGE,> 95% as determined by HPLC
• Form: Lyophilized
• Sequence: Ala20-Glu519
• Target: IL-31 RA

Images

Human IL-31 RA-on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-31 RA-is greater than 95% as determined by SEC-HPLC.

Immobilized Human IL-31, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-31 RA, hFc Tag with the EC50 of 1.53ug/ml determined by ELISA (QC Test).

Immobilized Human IL-31 RA, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA.

Human IL-31 RA, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-31, His Tag with an affinity constant of 1.97 nM as determined in SPR assay (Biacore T200).