The MET protooncogene was discovered because of the ability of oncogenic Met to mediate chemically induced transformation of a human osteogenic sarcoma cell line (1). This receptor tyrosine kinase is synthesized as a single-chain precursor, which undergo
Other: 1) Screening inhibitors or activators of recombinant catalytic domain of Met. 2) Detecting the effects of pharmacological agents on recombinant catalytic domain of Met.
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