Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 µM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia[1].
Molecular Weight:
231.29
CAS Number:
[515-49-1]
Formula:
C7H9N3O2S2
Target:
Antifolate,Fungal
Application Notes:
MCE Product type: Reference compound
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