Semagacestat (Standard) is the analytical standard of Semagacestat. This product is intended for research and analytical applications. Semagacestat is a gamma-secretase inhibitor, inhibits beta-amyloid (Abeta42), Abeta38 and Abeta40 with IC50s of 10.9, 12 and 12.1 nM, respectively, also inhibits Notch signaling with IC50 of 14.1 nM. Semagacestat can be used for the research of alzheimers?disease[1].
