Varenicline (Standard) is the analytical standard of Varenicline. This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of alpha4beta2 nicotinic acetylcholine receptor (alpha4beta2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of alpha6beta2 nAChR and a full agonist of alpha7beta2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation[1][2][3][4][5].
Molecular Weight:
211.268
CAS Number:
[249296-44-4]
Formula:
C13H13N3
Target:
nAChR,Reference Standards
Application Notes:
Reference Standards
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