TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. TPEN has a higher affinity for Zn2+, but a lower affinity for Mg2+ and Ca2+. TPEN induces DNA damage and increases intracellular ROS production. TPEN also inhibits cell proliferation and induces apoptosis[1][2][3].
Molecular Weight:
424.55
Purity:
99.91
CAS Number:
[16858-02-9]
Formula:
C26H28N6
Target:
Apoptosis,Autophagy,Reactive Oxygen Species (ROS)
Application Notes:
Reference compound
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