SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1][2].
Molecular Weight:
312.37
Purity:
99.14
CAS Number:
[68181-17-9]
Formula:
C12H12N2O4S2
Target:
ADC Linker
Application Notes:
ADC Related
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