SZL P1-41 is a specific Skp2 inhibitor, binds to the F-box domain of Skp2 to prevent Skp1 association and Skp2 SCF complex formation. SZL P1-41, like Skp2 deficiency, augments p27-mediated apoptosis/senescence, while it impairs Akt-driven glycolysis. Anti-tumor activities[1][2].
Molecular Weight:
420.52
Purity:
99.07
CAS Number:
[222716-34-9]
Formula:
C24H24N2O3S
Target:
Apoptosis,E1/E2/E3 Enzyme
Application Notes:
MCE Product type: Reference compound
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