Mifobate (SR-202) is a potent and specific PPARgamma antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARgamma transcriptional activity (IC50=140 µM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARalpha, PPARbeta, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects[1].
Molecular Weight:
358.65
Purity:
99.85
CAS Number:
[76541-72-5]
Formula:
C11H17ClO7P2
Target:
PPAR
Application Notes:
MCE Product type: Reference compound
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