RPR107393 free base, CAS [[197576-78-6]]

Product Overview

• Article Name: RPR107393 free base, CAS [[197576-78-6]]
• Biozol Catalog Number: MCE-HY-100299
• Supplier Catalog Number: HY-100299
• Alternative Catalog Number: MCE-HY-100299-1MG,MCE-HY-100299-5MG,MCE-HY-100299-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

RPR107393 free base is an orally active potent selective squalene synthase (SQS) inhibitor. RPR107393 free base inhibits rat liver microsomal squalene synthase with an IC50 value of 0.8 nM. RPR107393 free base reduces triglyceride biosynthesis by suppressing fatty acid biosynthesis via an increase in intracellular farnesol and its derivatives. RPR107393 free base reduces plasma cholesterol in rats and marmosets. RPR107393 free base can be used for metabolic disease research, such as hypercholesterolemia, hypertriglyceridemia and atherosclerosis[1][2].

Product Properties

• Molecular Weight: 330.42
• CAS Number: [197576-78-6]
• Formula: C22H22N2O
• Target: Farnesyl Transferase

Application Notes

• Application Notes: MCE Product type: Reference compound