FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively.
Molecular Weight:
428.34
Purity:
98.00
CAS Number:
[239440-20-1]
Formula:
C17H19Cl2N5O2S
Target:
Na+/H+ Exchanger (NHE)
Application Notes:
Reference compound
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