YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo[1]. YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent[2]. YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation[3].
Molecular Weight:
372.86
Purity:
99.37
CAS Number:
[182959-33-7]
Formula:
C21H22ClFN2O
Target:
Farnesyl Transferase,HCV
Application Notes:
Reference compound
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