cis-SU4312 ((Z)-SU4312) inhibits PDGFR and FLK-1 with IC50s of 19.4 and 0.8 µM, respectively. cis-SU4312 inhibits PDGFR, FLK-1, EGFR, HER-2, and IGF-1R with IC50s of 24.2, 5.2, 18.5, 16.9 and 10.0 µM, respectively. cis-SU4312 can cross blood brain barrier[1].
Molecular Weight:
264.32
CAS Number:
[90828-16-3]
Formula:
C17H16N2O
Target:
PDGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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