TTA-P2 (T-Type calcium channel inhibitor) is a selective, orally active, and BBB-penetrant T-type calcium channel blocker (IC50 = 22 nM). TTA-P2 reduces mechanical hypersensitivity and alleviates acute as well as chronic pain. TTA-P2 significantly reduces firing rates in temporal lobe epilepsy (TLE) neurons to control levels and suppresses synaptically evoked burst firing. TTA-P2 can be studied in research for neurological diseases such as tremor and absence epilepsy[1][2][3][4][5].
Molecular Weight:
431.37
Purity:
99.58
CAS Number:
[1072018-68-8]
Formula:
C21H29Cl2FN2O2
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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