Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity[1][2].
Molecular Weight:
255.22
Purity:
99.90
CAS Number:
[1577222-14-0]
Formula:
C11H13NO6
Target:
Keap1-Nrf2
Application Notes:
Reference compound
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