Nigericin (sodium salt), CAS [[28643-80-3]]

Product Overview

• Article Name: Nigericin (sodium salt), CAS [[28643-80-3]]
• Biozol Catalog Number: MCE-HY-100381
• Supplier Catalog Number: HY-100381
• Alternative Catalog Number: MCE-HY-100381-10MG,MCE-HY-100381-5MG,MCE-HY-100381-50MG,MCE-HY-100381-25MG,MCE-HY-100381-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/beta-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1/GSDMD in TNBC[1][2][3][4][5][6][7].

Product Properties

• Molecular Weight: 746.94
• Purity: 99.37
• CAS Number: [28643-80-3]
• Formula: C40H67NaO11
• Target: Antibiotic,Bacterial,NOD-like Receptor (NLR),Potassium Channel,Pyroptosis,Wnt,beta-catenin

Application Notes

• Application Notes: Natural Products