BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.40.2 µM in FP assay. BH3I-1 has a Kd of 5.3 µM against the p53/MDM2 pair.
Molecular Weight:
400.31
Purity:
98
CAS Number:
[300817-68-9]
Formula:
C15H14BrNO3S2
Target:
Bcl-2 Family,E1/E2/E3 Enzyme,MDM-2/p53
Application Notes:
Reference compound
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