Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer[1].
Molecular Weight:
421.62
Purity:
98.99
CAS Number:
[133825-80-6]
Formula:
C27H39N3O
Target:
Acyltransferase,Apoptosis
Application Notes:
Reference compound
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