Pactimibe (sulfate), CAS [[608510-47-0]]

Product Overview

• Article Name: Pactimibe (sulfate), CAS [[608510-47-0]]
• Biozol Catalog Number: MCE-HY-100401A
• Supplier Catalog Number: HY-100401A
• Alternative Catalog Number: MCE-HY-100401A-10MMX1ML,MCE-HY-100401A-50MG,MCE-HY-100401A-5MG,MCE-HY-100401A-25MG,MCE-HY-100401A-10MG,MCE-HY-100401A-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: CS-505

Product Description

Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 µM and 3.0 µM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 µM, 2.7 µM, 4.7 µM in the liver, macrophages and THP-1 cells, respectively[1]. Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 µM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 µM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity[2].

Product Properties

• Molecular Weight: 465.65
• Purity: 98
• CAS Number: [608510-47-0]
• Formula: C25H40N2O3.1/2H2O4S
• Target: Acyltransferase

Application Notes

• Application Notes: Reference compound