Pactimibe (sulfate) (Standard), CAS [[608510-47-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-100401AR
Supplier Catalog Number:
HY-100401AR
Alternative Catalog Number:
MCE-HY-100401AR-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate) (HY-100401A). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 µM and 3.0 µM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 µM, 2.7 µM, 4.7 µM in the liver, macrophages and THP-1 cells, respectively[1]. Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 µM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 µM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity[2].
Molecular Weight:
465.65
CAS Number:
[608510-47-0]
Formula:
C25H40N2O3.1/2H2O4S
Target:
Acyltransferase,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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