Ro 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM[1][2]. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM)[3].
Molecular Weight:
319.39
Purity:
99.69
CAS Number:
[298690-60-5]
Formula:
C17H18FNO2S
Target:
mGluR
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
