Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor. IC50: In Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 µM, 30 µM, respectively[1]. In Vivo:
Molecular Weight:
428.29
Purity:
95.98
CAS Number:
[1642300-78-4]
Formula:
C17H10F6N6O
Target:
CRM1
Application Notes:
Reference compound
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