NTU281 is a potent transglutaminase-2 inhibitor. NTU281 can reduce the increases in serum creatinine and albuminuria in diabetic rats. NTU281 can also reduce glomerular collagen I accumulation, Hic-5 and alpha-SMA expression, and apoptosis. NTU281 can be used for researching glomerulosclerosis caused by diabetes[1][2].
Molecular Weight:
487.59
CAS Number:
[815619-12-6]
Formula:
C25H31N2O6S
Target:
Apoptosis,Glutaminase
Application Notes:
Reference compound
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