AL-8810 is a potent and selective antagonist of the PGF 2alpha receptor (FP receptor). AL-8810 is an activator of MAPK and ERK1/2. The Ki of the FP receptor of mouse 3T3 cells and rat A7r5 cells are 0.20.06 µM and 0.40.1 µM, respectively. AL-8810 can be used in the study of elevated intraocular pressure (OHT) and primary open-angle glaucoma (POAG)[1][2][3][4][5].
Molecular Weight:
402.50
Purity:
99.00
CAS Number:
[246246-19-5]
Formula:
C24H31FO4
Target:
ERK,p38 MAPK,Prostaglandin Receptor
Application Notes:
Reference compound
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