GSK3179106 is an orally active and selective RET kinase inhibitor with IC50s of 0.4 nM, 0.2 nM for human RET and rat RET, respectively. GSK3179106 has the potential for irritable bowel syndrome (IBS) through the attenuation of post-inflammatory and stress-induced visceral hypersensitivity[1].
Molecular Weight:
467.41
Purity:
99.81
CAS Number:
[1627856-64-7]
Formula:
C22H21F4N3O4
Target:
RET
Application Notes:
Reference compound
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