TP-472, a chemical probe, is a selective BRD9/7 inhibitor, with Kds of 33 nM and 340 nM for BRD9 and BRD7, respectively. TP-472 exhibits >30-fold selectivity for BRD9 over other bromodomain family members except BRD7[1][2]. TP-472 induces apoptosis of melanoma cells[3].
Molecular Weight:
333.38
Purity:
99.54
CAS Number:
[2079895-62-6]
Formula:
C20H19N3O2
Target:
Apoptosis,Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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