Sp-cAMPS, a cAMP analog, is potent activator of cAMP-dependent PKA I and PKA II. Sp-cAMPS is also a potent, competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 µM. Sp-cAMPS binds the PDE10 GAF domain with an EC50 of 40 µM[1][2][3].
Molecular Weight:
345.27
CAS Number:
[71774-13-5]
Formula:
C10H12N5O5PS
Target:
Phosphodiesterase (PDE),PKA
Application Notes:
Reference compound
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