IWP-3 is an potent inhibitor of Wnt production with an IC50 of 40 nM. IWP-3 inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins. IWP-3 inhibits CK1gamma3 and CK1epsilon only moderately and does not inhibit CK1alpha[1][2].
Molecular Weight:
484.59
Purity:
99.27
CAS Number:
[687561-60-0]
Formula:
C22H17FN4O2S3
Target:
Wnt
Application Notes:
MCE Product type: Reference compound1
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