D-alpha-Hydroxyglutaric acid (disodium), CAS [[103404-90-6]]

Product Overview

• Article Name: D-alpha-Hydroxyglutaric acid (disodium), CAS [[103404-90-6]]
• Biozol Catalog Number: MCE-HY-100542
• Supplier Catalog Number: HY-100542
• Alternative Catalog Number: MCE-HY-100542-500MG,MCE-HY-100542-10MG,MCE-HY-100542-50MG,MCE-HY-100542-25MG,MCE-HY-100542-10MMX1ML,MCE-HY-100542-5MG,MCE-HY-100542-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: Disodium (R)-2-hydroxyglutarate

Product Description

D-alpha-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-alpha-Hydroxyglutaric acid disodium is a weak competitive antagonist of alpha-ketoglutarate (alpha-KG) and inhibits multiple alpha-KG-dependent dioxygenases with a Ki of 10.87 mM. D-alpha-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-alpha-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling[1][2][3][4][5].

Product Properties

• Molecular Weight: 192.08
• Purity: 98
• CAS Number: [103404-90-6]
• Formula: C5H6Na2O5
• Target: ATP Synthase,Endogenous Metabolite,mTOR,Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: MCE Product type: Reference compound