GSK-LSD1, a chemical probe, is a LSD1 inhibitor. GSK-LSD1 reduces food intake and body weight, and improves insulin sensitivity and glycemic control in mouse models of obesity. GSK-LSD1 also ameliorates NAFLD. GSK-LSD1 inhibits SARS-CoV-2-triggered cytokine release in COVID-19 PBMCs. GSK-LSD1 also inhibits cancer growth and metastasis[1][2][3].
Molecular Weight:
216.32
CAS Number:
[1431368-48-7]
Formula:
C14H20N2
Target:
Histone Demethylase
Application Notes:
MCE Product type: Reference compound1
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