IEM-1754, a dicationic adamantane derivative, is a potent blocker of open channels of native ionotropic glutamate receptors including quisqualate-sensitive receptors in insect muscles, NMDAR in cultured rat cortical neurons, and AMPAR in freshly isolated hippocampal cells. IEM-1754 shows anticonvulsant potency in vivo[1][2].
Molecular Weight:
412.25
Purity:
98.44
CAS Number:
[162831-31-4]
Formula:
C16H32Br2N2
Target:
iGluR
Application Notes:
MCE Product type: Reference compound1
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